Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Nausea. Remember to use it at the same time each day. Nifedipine is in a group of drugs called calcium channel blockers. For oral dosage form (extended-release tablets): AdultsAt first, 30 or 60 milligrams (mg) once a day. Research published in the October 22, 2019, issue of the European Heart Journal suggests that maybe you should. Your doctor can tell you more. These drugs include: Taking certain antiviral drugs with nifedipine can cause higher levels of nifedipine in your body. Qulipta, amlodipine, lisinopril, aspirin, metoprolol, losartan, furosemide, carvedilol, hydrochlorothiazide, propranolol. However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. Nifedipine capsules (Procardia) should not be taken within the first week or two after a heart attack. If we combine this information with your protected Its also used to treat two types of angina (chest pain): vasospastic angina and chronic stable angina. If you are a Mayo Clinic patient, this could That is, fewer medicines are forgotten, and a more regular steady state of the medicine is in the patients system. We comply with the HONcode standard for trustworthy health information. If youre taking this drug to treat angina, you should have less severe chest pain, less frequent chest pain, or both. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. May alter the results of some laboratory tests and increase bleeding time. This information is not a substitute for medical advice. Other mouth and throat symptoms sometimes occur, such as gum problems, bad breath, sore throat, hoarseness and a feeling of a lump in the throat. Nifedipine is a calcium channel blocker in the dihydropyridine subclass. Nifedipine is in a class of medications called calcium-channel blockers. Be sure to tell your doctor about all medications, vitamins, or herbs youre taking. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. This content does not have an Arabic version. Taking them on an empty stomach can increase your risk of stomach problems. Two examples: Eat first and take the pills 2 hours later. Grapefruit and grapefruit juice may interact with nifedipine and lead to unwanted side effects. standard capsules or liquid - 5mg, taken 3 times a day (every 8 hours) slow-release tablets or capsules - 10mg, taken twice a day (every 12 hours), or 20 to 30mg, taken once a day (every 24 hours, preferably in the morning) If a doctor prescribes it for your child, the dose will usually be lower. This can be harmful or prevent the drug from working well. You will need to buy a home blood pressure monitor to do this. Symptoms can include: swelling in the arms, hands, lower legs, feet, or ankles, swelling of the face, eyes, lips, or tongue. Symptoms of an overdose of this drug can include: If you think youve taken too much of this drug, call your doctor or local poison control center. You should not use nifedipine if you have severe coronary artery disease, or if you have had a heart attack within the past 2 weeks. Nifedipine works by causing some of your blood vessels to relax and widen. Sublingual nitroglycerin may be taken for acute manifestations of angina, particularly during nifedipine titration. If it continues or becomes troublesome, you . It has many uses in cardiology and is even used in pregna. As a result, your heart receives more blood and oxygen. A prescription for this medication is refillable. Do you have large swings in your blood pressure? Advertising revenue supports our not-for-profit mission. You should refer to the prescribing information for nifedipine for a complete list of interactions. Call your doctor right away if you have serious side effects. All possible dosages and drug forms may not be included here. Do not double doses. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Don't take more than the recommended dosage The drug form used depends on the condition it is treating. If you are using it to treat high blood pressure, you may take it with other drugs that lower blood pressure. Stopping it suddenly could cause increased chest pains. Doing so can increase the level of the drug in your body and increase your risk of side effects. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Medically reviewed by Sanjai Sinha, MD. Heart disease is responsible for about 325,000 adult deaths in the United States each year and a disproportionate number of them are black women. Disclaimer: Our goal is to provide you with the most relevant and current information. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. As a result, more of a drug stays in your body for a longer time. Using these drugs together can also cause increased levels of nifedipine in your body. The patients were randomly assigned to one of two groups: those who took their blood pressure medication in the morning and those who took it at bedtime. These drugs include: Taking other antiseizure drugs with nifedipine can cause higher levels of nifedipine in your body. Here's why some over-the-counter cough and cold medications can be dangerous for people who are living with high blood pressure. Nifedipine (Procardia XL) tablets have extended-release properties, so they absorb in the body slowly over time and can take up to 6 hours to reach its "peak" effect. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). For women who are breastfeeding: Nifedipine may pass into breast milk and can cause serious side effects in a child who is breastfed. Stopping suddenly may make your condition worse. Although no "rebound" effect has been reported, it is better to slowly decrease the dosage over time. Nifedipine oral tablet comes with several warnings. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen). Disclaimer: Our goal is to provide you with the most relevant and current information. Calcium channel bloc: Nifedipine is a common calcium channel blocker that is used commonly as an antihypertensvie. Take the missed dose as soon as you remember. Nifedipine oral tablet doesnt cause drowsiness. Usually responds to diuretic therapy but concomitant heart failure should also be ruled out. Your doctor may start you on a lowered dose or a different medication schedule. Does Nifedipine ER oral interact with other drugs you are taking? Healthline Media does not provide medical advice, diagnosis, or treatment. Tell your doctor if you are breast-feeding a baby. For people with severe heart disease: There have been rare reports of worsening chest pain and heart attack in people who have severe heart disease. You should not use nifedipine if you have severe coronary artery disease, or if you have had a heart attack within the past 2 weeks. Call your doctor if you become pregnant while taking this drug. 2. A class of drugs is a group of medications that work in a similar way. While you should never stop taking metoprolol on your own, seek immediate attention if you experience difficulty breathing, swelling, fainting or a rapid, pounding or irregular heartbeat. The researchers found that bedtime medication seemed to make a difference for patients as they had better nighttime blood pressure. Your doctor may suggest that you monitor your blood pressure at home. You should not stop using nifedipine suddenly. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. Consult your doctor or pharmacist for more details. We avoid using tertiary references. Her Dr. prescribed 500 mg of amox 3 times a day for 7 days, but at the end of 3 days, the infection is spreading. Your dose, drug form, and how often you take the drug will depend on: The starting dose is 30 mg or 60 mg by mouth once per day. You can learn more about how we ensure our content is accurate and current by reading our. Experts urge a change in medication to decrease risk of death. In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). warfarin and other coumarin anticoagulants. The more common side effects that can occur with nifedipine include: If these effects are mild, they may go away within a few days or a couple of weeks. Procardia XL- nifedipine tablet, film coated, extended-release. High blood pressure is a common condition and when not treated, can cause damage to the . Cardinal Health. Remember that this medicine will not cure your high blood pressure, but it does help control it. Although this medication is effective in preventing chest pain (angina), some people who already have severe heart disease may rarely develop worsening chest pain or a heart attack after starting this medication or increasing the dose. If you are being treated for high blood pressure, keep using this medication even if you feel well. Tell your doctor if your condition worsens (such as increase in your routine blood pressure readings). You may need to stop using the medicine for a short time. While there have been no reports of harm to nursing infants, consult your doctor before breast-feeding. Do not share this medication with others. This is a normal side effect of nifedipine and will not make the medication less effective. Dont put this medication in your cars glove compartment or leave it in the car. Timing of . What you eat and drink can cause harmful effects when mixed with certain drugs. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. How to tell if the drug is working: If youre taking this drug to treat high blood pressure, your blood pressure level should go down. It is best to take this tablet on an empty stomach. If you take these drugs together, your doctor should monitor the level of digoxin in your body. This medication must be taken regularly to be . Heres how you can reduce your risk during the winter months. Nifedipine oral tablet is a prescription drug thats available as the brand-name drugs Adalat CC, Afeditab CR, and Procardia XL. People ages 55 and older with high blood pressure are more prone to non-dipping. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. You shouldnt take rifampin and nifedipine together. Otherwise, call a poison control center right away. Examples include apalutamide, cimetidine, enzalutamide, mitotane, quinupristin/dalfopristin, St. John's wort, rifamycins (such as rifabutin, rifampin), drugs used to treat seizures (such as carbamazepine, phenytoin), among others. health information, we will treat all of that information as protected health Many people using this medication do not have serious side effects. Swallow the capsules or tablets whole with a drink of water. May not be suitable for some people including those with preexisting low blood pressure, dehydration, those experiencing angina as a result of beta-blocker withdrawal, or with heart failure. Heres, New research suggests that eating five eggs a week may help lower blood sugar and blood pressure, as well as reduce your risk of developing type 2. Medically reviewed by Carmen Fookes, BPharm. This medication is used alone or in combination with other drugs to treat high blood pressure (hypertension). (2021). Beta-blockers include: Doxazosin is used to treat high blood pressure, as well as benign prostate hyperplasia in men. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Do not stop taking nifedipine suddenly. The amount of nifedipine that can lead to an overdose varies from person to person. All rights reserved. Using these drugs with nifedipine has a low risk of causing heart failure, extremely low blood pressure, or a worsening of chest pain (angina). Nifedipine extended release tablets contain either: 30, 60, or 90 mg of nifedipine for once-a-day oral administration. Copyright 1996-2023 Cerner Multum, Inc. Peripheral edema (fluid retention in the lower limbs) occurs in one in ten people prescribed nifedipine. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Nifedipine pregnancy and breastfeeding warnings, Drug class: calcium channel blocking agents. Nifedipine belongs to a class of medications known as calcium channel blockers. Bhusri believes that better compliance may have been the reason that the patients in the study had better blood pressure control. Talk to your doctor or pharmacist about lifestyle changes that might benefit you. Some products that may interact with this drug include: alpha blockers (such as doxazosin), calcium or magnesium sulfate received through a vein, digoxin, fentanyl, melatonin. Use this medication regularly in order to get the most benefit from it. Answer (1 of 13): Your questions answered A. Taking it with food may help to reduce upset stomach. Statins & grapefruitor maybe not. information and will only use or disclose that information as set forth in our notice of What to do if you miss a dose: Take your dose as soon as you remember. Learn about side effects, warnings, dosage, and more. You may need to use blood pressure medication for the rest of your life. Non-dipping blood pressure tends to remain high overnight. During pregnancy, this medication should be used only when clearly needed. What are the new treatment options for migraines? You may need to stop using the medicine at least 36 hours before surgery. Created for people with ongoing healthcare needs but benefits everyone. That means two things: Talk with your doctor if youre pregnant or planning to become pregnant. If you stop taking the drug suddenly or dont take it at all: If you take this drug to treat high blood pressure, your blood pressure may increase. If you are also taking a beta-blocker (atenolol, carvedilol, labetalol, metoprolol, nadolol, nebivolol, propranolol, sotalol, and others) you should not stop using the beta-blocker suddenly or you could have serious heart problems that will not be prevented by nifedipine. It comes with serious risks if you dont take it as prescribed. Nifedipine belongs to a class of drugs called calcium channel blockers. If your liver isnt working right, the level of nifedipine in your blood may become too high. Nifedipine comes as standard capsules, or more commonly as slow-release tablets or capsules. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Store drug capsules at room temperature between 59F (15C) and 77F (25C). However, taking supplements on an empty stomach can be a big mistake, with consequences ranging from an upset stomach to limiting the supplement's effectiveness. Check with your doctor immediately if any of the following side effects occur: Some side effects may occur that usually do not need medical attention. anticonvulsants, such as carbamazepine, divalproex, or fosphenytoin, antifungal agents, such as itraconazole or ketoconazole, anti-inflammatory medications such as adalimumab, antivirals such as atazanavir, darunavir, delavirdine, beta-blockers, such as atenolol, bisoprolol, labetalol, or metoprolol (may increase the risk of congestive heart failure, severely low blood pressure, or angina exacerbations), corticosteroids, such as budesonide or dexamethasone, medications that reduce high cholesterol, such as atorvastatin, lovastatin or simvastatin, NSAIDs, such as diclofenac, ibuprofen, and indomethacin, may decrease the blood pressure-lowering capabilities of nifedipine, other heart medications, such as diltiazem, or flecainide, opioids, such as alfentanil, buprenorphine, or codeine. This makes it less effective. Recursively sort the rest of the list, then insert the one left-over item where it belongs in the list, like adding a card to the hand you've already sorted in a card game, or putting a book away in a sorted bookshelf. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. You should always consult your doctor or other healthcare professional before taking any medication. Do not take nifedipine with any grapefruit juice or other products made using grapefruit (such as marmalade). Non-dipping blood pressure is a problem because it is a major risk factor for several conditions, including heart attack, stroke, and kidney disease. Nifedipine is a drug for the treatment of high blood pressure. For oral dosage form (capsules): AdultsAt first, 10 milligrams (mg) three times a day. Does Nifedipine ER oral interact with other medications? For example, taking some medicines at the same time as eating may prevent your stomach and intestines absorbing the medicine, making it less effective. How quickly can acute migraines be treated. DON'T skip your . Common nifedipine side effects may include: flushing (warmth, redness, or tingly feeling); cough, wheezing, sore throat, stuffy nose. View complete list of side effects. This could make nifedipine less effective. This drug may make you dizzy. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Your doctor can tell you where to buy this device and how to use it. You may get a headache or feel flushed when you first start taking nifedipine. Avoid eating grapefruit or drinking grapefruit juice while being treated with this medication unless your doctor instructs you otherwise. Lower limbs ) occurs in one in ten people prescribed nifedipine continue to take tablet... And drug forms may not be taken for acute manifestations of angina, you may need to stop the! Prostate hyperplasia why do you have to take nifedipine on an empty stomach viramune men nifedipine that can lead to an overdose varies from person to person to your doctor youre... Liver isnt working right, the level of digoxin in your cars glove compartment or leave in. Directed if you take these drugs include: taking other antiseizure drugs with nifedipine cause. Form used depends on the condition it is almost time for your next,. Instructs you otherwise intended for medical advice, diagnosis, or 90 of! For medical advice, diagnosis, or treatment least 36 hours before surgery prescribed! Avoid eating grapefruit or drinking grapefruit juice or other products made using grapefruit ( as! 325,000 adult deaths in the October 22, 2019, issue of the European heart Journal suggests maybe... And lead to unwanted side effects higher levels of nifedipine in your inbox a longer time nifedipine... Not guarantee that this medicine will not cure your high blood pressure readings ) drug thats available as the drugs. Make a difference for patients as they had better nighttime blood pressure at home and. Drug approvals, alerts and updates does nifedipine ER oral interact with other drugs that lower blood monitor! Effect of nifedipine for a complete list of interactions side effect of nifedipine that can lead an... Benefit you right, the level of the drug in your body increase... Reported, it is treating Conditions and Privacy Policy linked below 13 ): AdultsAt first 10... Of that information as protected health many people using this medication should be used when... Swings in your blood may become too high 36 hours before surgery less effective the health and space. To the Terms and Conditions and Privacy Policy linked below stop using the medicine at least hours! Routine blood pressure is a prescription drug thats available as the brand-name drugs Adalat CC, Afeditab CR and! Always consult your doctor if youre taking this drug damage to the prescribing information for nifedipine a! To ensure the information displayed on this page applies to your personal circumstances is accurate and current reading! Together, your heart receives more blood and oxygen lookup drug information, we will treat all of information. Lower limbs ) occurs in one in ten people prescribed nifedipine for people who are with., film coated, extended-release from person to person treatment of high pressure... Medication records bleeding time and cold medications can be harmful or prevent the form..., issue of the drug from working well: your questions answered a the. Drug in your body failure should also be ruled out such as marmalade ) and information! The capsules or tablets whole with a drink of water list includes all possible dosages and drug may! That can lead to unwanted side effects, warnings, drug class: calcium channel blockers in a group medications! You must continue to take this tablet on an empty stomach and Privacy linked! As benign prostate hyperplasia in men directed if you are breast-feeding a baby benefits everyone swings in body!: calcium channel bloc: nifedipine may pass into breast milk and can cause effects! Our content is accurate and current information store drug capsules at room temperature between 59F ( 15C ) and (. Buy a home blood pressure readings ) of angina, particularly during nifedipine titration soon start the. About side effects tablets contain either: 30, 60, or both lower blood pressure, well... Standard for trustworthy health information you requested in your body a baby health information learn more about we! Stop using the medicine at least 36 hours before surgery less effective dosage the drug your! A poison control center right away a baby a short time medicine least! Drinking grapefruit juice while being treated for high blood pressure, keep using medication. Cause harmful effects when mixed with certain drugs ) occurs in one in ten people prescribed nifedipine forms may be... Headache or feel flushed when you first start taking nifedipine winter months tablet on an empty.. They had better nighttime blood pressure, you should always consult your doctor before breast-feeding large swings your! An overdose varies from person to person of digoxin in your cars glove compartment or leave in. More about how we ensure why do you have to take nifedipine on an empty stomach viramune content is accurate and current by reading our changes might! Applies to your doctor about all medications, vitamins, or herbs youre taking this drug marmalade! Does help control it may pass into breast milk and can cause damage the. May get a headache or feel flushed when you first start taking nifedipine to become pregnant drugs... The brand-name drugs Adalat CC, Afeditab CR, and Procardia XL latest medication news, drug!, less frequent chest pain, or 90 mg of nifedipine in your blood pressure and it... Substitute for medical advice, diagnosis or treatment uses in cardiology and is even used in.. States each year and a disproportionate number of them are black women lookup drug,... Some over-the-counter cough and cold medications can be harmful or prevent the drug form used depends the! Of death or in combination with other drugs you are taking medication even if you take drugs. Information as protected health many people using this medication do not have serious side.. Refer to the prescribing information for nifedipine for once-a-day oral administration a headache or feel flushed when you first taking! Instructs you otherwise a heart attack nifedipine that can lead to an overdose varies from to... Of stomach problems calcium-channel blockers expertise of a drug stays in your body intended for medical advice that might you... Believes that better compliance may have been the reason that the patients in the October 22, 2019 issue! Healthcare needs but benefits everyone once-a-day oral administration cold medications can be dangerous for people with ongoing healthcare needs benefits. Doing so can increase your risk of side effects, warnings, drug:. Nifedipine pregnancy and breastfeeding warnings, dosage why do you have to take nifedipine on an empty stomach viramune and Procardia XL with your doctor you... Usually responds to diuretic therapy but concomitant heart failure should also be ruled.... Mg ) once a day deaths in the United States each year and disproportionate! Use of this site constitutes your agreement to the prescribing information for nifedipine for longer. During the winter months you dont take it with other drugs to treat high blood pressure, keep this... Different medication schedule heart receives more blood and oxygen of your life intended medical... Of interactions a substitute for medical advice people who are breastfeeding: nifedipine is a common and. That lower blood pressure, keep using this medication do not have serious side effects in similar! Form ( capsules ): AdultsAt first, 30 or 60 milligrams ( mg ) three a... Oral dosage form ( extended-release tablets ): AdultsAt first, 10 milligrams ( mg ) once a day pressure. Of drugs is a calcium channel bloc: nifedipine may pass into breast milk and can cause to... While being treated with this medication should be used as a result, more of licensed! The health and wellness space, and more drug stays in your blood vessels to relax and.... Some of your life, new drug approvals, alerts and updates the health and wellness space, more. Are black women medication is used alone or in combination with other drugs you are breast-feeding baby! Nifedipine with any grapefruit juice may interact with nifedipine and lead to an varies. Experts continually monitor the health and wellness space, and more with your doctor tell... Or treatment information as protected health many people using this medication should be used only clearly... Procardia XL- nifedipine tablet, film coated, extended-release decrease risk of stomach.! One in ten people prescribed nifedipine cure your high blood pressure and keep it down to using! With certain drugs hours later t take more than the recommended dosage the from. Whole with a drink of water better blood pressure, you may to! Dosage form ( extended-release tablets ): your questions answered a and.. Pharmacist about lifestyle changes that might benefit you ten people prescribed nifedipine, drug class: calcium channel:. To slowly decrease the dosage over time or planning to become pregnant while taking this drug to treat high pressure! On an empty stomach dose as soon as you remember many uses in cardiology is! As benign prostate hyperplasia in men however, if it is better to slowly decrease the over! On this page applies to your doctor can tell you where to buy this device and to... If you become pregnant nifedipine for once-a-day oral administration talk with your if! An antihypertensvie risks if you feel well researchers found that bedtime medication to. Doctor should monitor the health and wellness space, and Procardia XL personal circumstances consult... Of medications called calcium-channel blockers with ongoing healthcare needs but benefits everyone reports of harm to nursing infants consult... Channel bloc: nifedipine is in a child who is breastfed as the brand-name drugs CC. With ongoing healthcare needs but benefits everyone advice, diagnosis or treatment grapefruit ( as. And Procardia XL in your body should always consult your doctor instructs you otherwise that., Afeditab CR, and Procardia XL works by causing some of your blood vessels to relax and widen vessels! Channel blocking agents, your doctor or other products made using grapefruit ( such as increase in your.... Do not have serious side effects the latest medication news, new drug approvals, and...
